NewsLFC fitness update: Roberto Firmino, Naby Keita, Diogo Jota and Curtis Jones
Firmino has trained normally in the build-up to Liverpool's trip to Old Trafford after sitting out Monday's draw with Crystal Palace as a precaution.
Keita, meanwhile, returned to the matchday squad for the Anfield encounter but was an unused substitute following a period of illness.
Offering a fitness update during his pre-match press conference, Klopp said: "Yeah, Bobby trained completely normal, is ready."
He later added: "Naby was ill for a week, last game on the bench, is fully in training, looks really good. All fine."
The Reds boss also reported no fresh injury concerns within his squad, though remains without Joel Matip, Thiago Alcantara, Ibrahima Konate, Curtis Jones, Diogo Jota, Alex Oxlade-Chamberlain, Calvin Ramsay and Caoimhin Kelleher.
"All the others trained normal as well. No, nobody came back," Klopp said.
Asked about Jones and Jota in particular, he reported: "Getting closer. Ask after the game again but no chance for this game."
NewsLoan watch: Seven Liverpool players involved on Saturday
Stream2pm GMT: Live Women's League Cup football - watch Newcastle v Liverpool
AcademyU18s match report: Comeback at Birmingham sends Liverpool to PL Cup quarter-finals
MatchThe opposition lowdown: Southampton
Interview'We can't take our foot off the gas' - Caoimhin Kelleher previews Southampton v Liverpool