Steven Gerrard needs just two goals to register 100 in the top-flight for Liverpool.
The skipper would become the 12th Reds player to score 100 league goals for Liverpool - the last was Michael Owen in April 2003.
The No.8 has only scored once for Liverpool in 34 appearances against Chelsea. His strike in October 2005 came in a 4-1 defeat at Anfield.
Here are more facts and figures ahead of Sunday's Anfield clash with club statto Ged Rea...
Earlier this season the sides drew 1-1 at Stamford Bridge. John Terry's 50th goal in his 558th appearance and his first in 33 games against Liverpool gave the Londoners the lead but Luis Suarez equalised with 17 minutes remaining.
The last meeting at Anfield, saw Liverpool win 4-1 last May. They led 3-0 after 28 minutes with goals from Michael Essien (OG), Jordan Henderson and Daniel Agger. Stewart Downing then missed a penalty on the stroke of half-time. Ramires pulled one back before Jonjo Shelvey scored his first league goal for the Reds.
The Reds are unbeaten in the last five league meetings since Chelsea won 2-0 at Anfield in May 2010 with goals from Didier Drogba and Frank Lampard.
Liverpool have won six of the last nine league meetings home and away and have lost just two of the last 12.
Glen Johnson made his Chelsea debut against Liverpool at Anfield in 2003. He went on to appear on 72 occasions for the club in all competitions from 2003-2007 scoring four times.
Patrik Berger scored Liverpool's last hat-trick against Chelsea at Anfield in October 1997 in a 4-2 win. He is one of four Liverpool hat-trick scorers in the league against the Londoners. The others were James Stewart in 1910, Fred Pagnam (1915) and Gordon Hodgson (1930).
The Reds have failed to score in only two of the last 32 home league meetings with Chelsea.
Liverpool's biggest league victory over Chelsea here came in April 1935 when they won 6-0.
This will be Jamie Carragher's 45th and final game against Chelsea. He has made more appearances for Liverpool against the Londoners than other Reds player ever while Steven Gerrard is second on the list with (34).
Luis Suarez is without a goal in his last four league games. He requires one to become only the 11th different player to achieve the milestone of 30 goals in a season for the club.
Jordan Henderson made his career league debut against Chelsea in November 2008. His Sunderland team lost 5-0 at Stamford Bridge.
Martin Skrtel's next appearance will be his 150th for Liverpool in the Premier League.
Daniel Agger has scored 11 goals for Liverpool. Chelsea are the only team he has scored more than once against - in the league in May 2012 and the Champions League semi-final in May 2007.
Liverpool have won each of the seven games in which Stewart Downing has scored.
Daniel Sturridge scored 24 goals in 96 appearances for Chelsea from 2009-13 including 13 in 63 league games. He scored for Chelsea in the Reds 2-1 victory at Stamford Bridge in November 2011.
He played the last eight minutes of this season's meeting at Stamford Bridge as a substitute for Fernando Torres.
This game will be Liverpool's 50th game in all competitions under Brendan Rodgers.
18 different players have scored this season for the Reds, equalling the club record.
Liverpool's last two league games have finished 0-0 (against West Ham and Reading). They have never played out three successive goalless draws.
The last time they failed to score in three successive games was in October 2009 while the last time they failed to hit the net in three league games in a row was March 2005.
Liverpool have kept 13 clean sheets in the league this season - the second best tally in the top-fight, two fewer than Manchester City.
The Reds are looking to record a third successive home league win over Chelsea for the first time since 1997-98.
Chelsea have scored eight times against Liverpool in the last 12 league meetings home and away.
Chelsea have won nine times on this ground in the league with four of those victories coming in the last nine years.
Fernando Torres scored seven goals in eight appearances for Liverpool against his current club and has played five times since against the Reds.
Only two players have ever scored more goals for Liverpool against Chelsea than Fernando Torres (seven) - Ian Rush (10) and Roger Hunt (nine).
Rafael Benitez returns to Anfield as a manager for the first time since leaving in 2010. He won 55 per cent of his 228 league games in charge of Liverpool.
The last time he managed a team at Anfield the opposition were Chelsea - May 2010.
He has won his two previous games as coach of a team against the Reds - with Valencia in the Champions League in 2002.
For Chelsea Frank Lampard has scored one goal in his last 10 games after netting nine in his previous 13 starts.
He has scored eight times in 43 games against Liverpool during his club career with West Ham and Chelsea.
Torres has scored 20 goals in all competitions this season including seven in the league. He has four goals in his last five starts but has not scored in the league since December 23 when Villa were beaten 8-0.
Chelsea have scored more goals than any other team in all four divisions. They have found the net 129 times.
They have scored 29 goals on the road in the league this season, the same as Liverpool. Only Manchester United 35 and Tottenham 31 have scored more.
Chelsea have lost five away games this season in the league - at West Brom (2-1), West Ham (3-1), Newcastle (3-2), Man City (2-0) and Southampton (2-1).
Chelsea will play a minimum of 68 games this season. They have reached the semi-finals of the FA Cup, League Cup and Europa League.
Since Benitez was put in charge of Chelsea he has presided over 39 games, winning 21 and losing 10.
In the league he has won 11 and lost five of his 20 games as interim manager.